Neutrons reveal hidden secrets of the hepatitis C virus
• p7 is a protein essential for the release of the hepatitis C virus, however little data is currently available on the way it interacts with its environment, hindering the development of vaccinations for it
• Researchers have observed the structure of a functional p7 protein within its native environment for the first time using reflected neutrons
• The specific protein insertion mechanism observed will help to outline potential target mechanisms for future drug development
Erik Watkins, former ILL FIGARO Instrument Scientist, said: “This new approach is a simple and efficient method complementary to other structural and more complex techniques such as NMR and crystallography. This has proved a powerful tool for characterising...