Zoe Fisher
Senior Scientist for Chemistry and Life Science Support
Scientific Activities Division
Science Directorate
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MailZoe.Fisher [at] ess.eu
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LinkedIn
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Research Gate
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ORCID
Selected Publications
(2024-2019)
- Koruza, K., Krupinska, E., Sele, C.P., Vegvari, A., Knecht, W., Fisher, S.Z. (2024) “Botryococcus braunii autolysate for the production of deuterium-labeled recombinant protein.” Algal Research 79, p.103459, doi:10.1016/j.algal.2024.103459
- Sele, C., Krupinska, E., Andersson Rasmussen, A., Ekström, S., Hultgren, L, Lou, J., Kozielski, F., Fisher, S.Z., Knecht, W. (2024) “New insights into complex formation by SARS-CoV-2 nsp10 and nsp14”, Nucleos. Nucleot. Nucl., p.1-15, doi:10.1080/15257770.2024.2321600
- Knecht, W., Fisher, Z., Lou, J., Sele, C., Ma, S., Andersson Rasmussen, A., Pinotsis, N., Kozielski, F., (2023) “Oligomeric state of β-coronavirus non-structural protein 10 stimulators studied by Small Angle X-ray Scattering.”, Int. J. Mol. Sci. 24, p.13649. doi:10.3390/ijms241713649.
- Raum, H.N., Fisher, S.Z., Weininger, U. (2023) “Energetics and dynamics of the Proton Shuttle of Carbonic Anhydase II”, Cell. Mol. Life Sci. 80, art. 286, doi.org/10.1007/s00018-023-04936-z
- Sørensen, H.V.,Montserrat-Canals, M., Loose, J.S.M., Fisher, Z., Moulin, M., Blakeley, M.P., Cordara, G., Bjerregaard-Andersen, K., Krengel, U. (2023) “Perdeuterated GbpA enables neutron scattering experiments of a lytic polysaccharide monooxygenase”, ACS Omega 8, p. 29101-29112. doi: 10.1021/acsomega.3c02168.
- Kozielski, F., Sele, C., Talibov, V.O., Lou, J., Dong, D., Wang, Q., Shi, X., Nyblom, M., Rogstam, A., Krojer, T., Fisher, Z., Knecht, W. (2022) “Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16”, RSC Chem. Biol. 3, p.44-55.
- Aggarwal, S., Wachenfeldt, C.V., Fisher, S.Z., Oksanen, E. (2021) “A protocol for production of perdeuterated OmpF porin for neutron crystallography”, Protein Expr Purif. 105954. doi: 10.1016/j.pep.2021.105954.
- Rogstam, A., Nyblom. M., Christensen, S., Sele, C., Talibov, V.O., Lindvall, T., Rasmussen, A.A., André, I., Fisher, S.Z., Knecht, W., Kozielski, F. (2020) “Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2” Int. J. Mol. Sci. 21, p.7375.
- Koruza, K., Murray, A.B., Mahon, B.P., Hopkins, J.B., Knecht, W., McKenna, R., Fisher, S.Z. (2020) “Biophysical Characterization of Cancer-Related Carbonic Anhydrase IX” Int. J. Mol. Sci. 21, p. 5277.
- Clabbers, M.T.B., Fisher, S.Z., Coinçon, M., Zou, X., Xu, H. (2020) “Visualizing drug binding interactions using microcrystal electron diffraction” Commun. Biol. 3: 417.
- Budayova-Spano, M., Koruza, K., Fisher, S.Z. (2020) “Large crystal growth for neutron protein crystallography” Methods Enzymol. 634, p.21-46.
- Koruza, K., Lafumat, B., Nyblom, M., Mahon, B.P., McKenna, R., Fisher, S.Z. (2019) “Structural comparison of protiated, H/D exchanged, and deuterated human carbonic anhydrase IX” Acta Cryst D75, p. 895-903.
- Koruza, K., Mahon, B.P., Blakeley, M.P., Ostermann, A., Schrader, T., Knecht, W., McKenna, R., Fisher, S.Z. (2019) “Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative” J. Struct. Biol. 205, p. 147-154.
Career History
Current position(s)
- Senior Scientist & Team leader for the Deuteration and Macromolecular Crystallization (DEMAX) platform, Scientific Activities Division (SAD), European Spallation Source (ESS), Lund, Sweden (2023 – present)
- Adjunct Senior Lecturer, Department of Biology & LP3, Lund University, Lund, Sweden (2016 – present)
Previous positions:
- Group leader (DEMAX), SAD at ESS in Lund, Sweden (2019-2022)
- Deputy Division Head, for SAD, ESS, Lund, Sweden (2017 – 2023)
- Research & support scientist, SAD at ESS in Lund, Sweden (2014 – 2018)
- Research Scientist II, Los Alamos National Laboratory (LANL), Los Alamos NM, USA (2010 – 2014)
- Postdoctoral Associate (2007-2010) at LANL, Los Alamos NM, USA (2007-2010)
Education
- Ph.D. in Biochemistry and Molecular Biology (2006). Title: Structural insights into the active site of alpha-carbonic anhydrases. Advisor: Dr. Robert McKenna, University of Florida (Gainesville FL, USA).
- B.Sc. (Hons) in Biochemistry (2000) under the supervision of Dr. Janet Hapgood, University of Stellenbosch (Stellenbosch, South Africa)
- B.Sc. double majored in Biochemistry and Animal Physiology (1999), University of Stellenbosch (Stellenbosch, South Africa)